Gene information retrieval. The user can provide an exact gene name or a fuzzy query term, such as disease association and some properties. The server will output the top nine relevant genes based on the gene’s summary from NCBI and show it on the screen.
Genomic visualization of a region related to a gene. Since it is not practical for a user to give the exact genomic location, we used gene-centered visualization. The user can visualize the genome information like a genome browser, including the histone marks signal, the TF binding signal, and other useful information. The user can also move forward and backward along the genome to search the surrounding regions of a gene. By providing a gene name, or selecting a gene from the gene query output, Gene Tracer can display the genomic landscape view around that gene. This view requires a bigger screen for better visualization of genomic information. You will only get voice response for Alexa Spot.
Mutation view to indicate the most deleterious mutations. The user can also use Gene Tracer to annotate mutations to find those that have highly deleterious effects, through a mutation view for browsing. Slightly different from gene-centered browsing, the user can find the coding and non-coding mutations from ClinVAR that strongly affect a gene’s function or regulation according to FunSeq2’s annotation. This view requires a bigger screen for better visualization of genomic information. You will only get voice response for Alexa Spot.
Network visualization. The user can also visualize the genes and their interacting partners using a network view. The server side includes a protein-protein interaction dataset (Stark, et al., 2006), and the R scripts depend on the igraph package (Nepusz, 2006). We recommend using a bigger screen for better visualization of network. The image on Alexa Spot maybe not clear for a dense network.
Exporting and revisiting the query history. The user can access their query history and figures once the session ends. The link will be presented on the screen and is accessible later on any desktop.
The gene tracer skill and information from gene tracer skill is provided for informational and educational purposes only. All information provided by gene tracer skill is provided in good faith, however we make no representation or warranty of any kind, express or implied, regarding the accuracy, adequacy, validity, reliability, availability or completeness of any information from the use of gene tracer skill.
Under no circumstance shall we have any liability to you for any loss or damage of any kind incurred as a result of the use of the gene tracer skill or reliance on any information provided on the gene tracer skill. Your use of the gene tracer skill and your reliance on any information on the gene tracer skill is solely at your own risk.
“Alexa, open Gene tracer and tell me gene related to breast cancer.”
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