This is a voice guide that discusses hypoactive sexual desire disorder, also known as HSDD. Hypoactive sexual desire disorder (HSDD) is defined as ongoing low sexual desire that results in frustration in women. This can make women lack intimacy, leading to issues around self-esteem and stress in relationships. It’s believed that the cause of HSDD is an imbalance of neurotransmitter (chemical messengers) activity in the brain, resulting in low sexual desire. Disclaimer – This content is intended for use by United States residents only. This content is for informational purposes only and is not intended to replace a discussion with a health care provider.